Modulation of CTCF insulator function by transcription of a noncoding RNA.
نویسندگان
چکیده
CTCF plays diverse roles in the regulation of eukaryotic genes. A new study by Lefevre et al. in a recent issue of Molecular Cell reveals a novel mechanism in which noncoding RNA transcription and nucleosome repositioning evicts CTCF from a regulatory element to facilitate induction of a nearby gene.
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ورودعنوان ژورنال:
- Developmental cell
دوره 15 4 شماره
صفحات -
تاریخ انتشار 2008